New England Patriots vs. Buffalo Bills NFL Week 16 Odds, Plays and Insights

Dec 22, 2021

Check out odds, plays and more for the New England Patriots vs. Buffalo Bills NFL Week 16 matchup on December 26, 2021.

The New England Patriots (9-5) face an AFC East matchup in Week 16 versus the Buffalo Bills (8-6).

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Odds for Patriots vs. Bills

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New England and its opponents have gone over the current 43.5-point total in seven of 14 games (50%) this season.
In 50% of Buffalo's games this season (7/14), the teams combined to score more than Sunday's total of 43.5.
Sunday's total is 10.8 points lower than the two team's combined 54.3 points per game average.
This contest's over/under is 9.9 points greater than the 33.6 these two squads combine to allow per game this season.
Patriots games this season feature an average total of 44.7 points, a number 1.2 points higher than Sunday's over/under.
The 48.2 PPG average total in Bills games this season is 4.7 points more than this game's over/under.

Against the spread, New England is 9-5-0 this year.
The Patriots are 6-3 ATS when favored by 2.5 points or more this season.
New England's games this year have gone over the point total in 42.9% of its opportunities (six times in 14 games with a set point total).
This year, the Patriots score 8.8 more points per game (26.2) than the Bills surrender (17.4).
New England is 7-2 against the spread and 8-1 overall this season when the team notches more than 17.4 points.
The Patriots average 60.0 more yards per game (347.9) than the Bills allow per matchup (287.9).
New England is 6-5 against the spread and 6-5 overall when the team churns out more than 287.9 yards.
The Patriots have turned the ball over 18 times this season, nine fewer than the Bills have forced (27).
Click over to SISportsbook and find the latest spread, moneyline and total for New England's matchup with the Bills.

Buffalo has eight wins against the spread in 14 games this year.
This season, the Bills have one against the spread win in two games as an underdog of 2.5 points or more.
Buffalo has eclipsed the over/under in 50% of its opportunities this year (seven times in 14 games with a set point total).
The Bills rack up 28.1 points per game, 11.9 more than the Patriots surrender (16.2).
When Buffalo records more than 16.2 points, it is 8-2 against the spread and 8-2 overall.
The Bills collect 70.4 more yards per game (377.9) than the Patriots give up per contest (307.5).
When Buffalo churns out more than 307.5 yards, the team is 8-4 against the spread and 8-4 overall.
This season the Bills have 19 turnovers, eight fewer than the Patriots have takeaways (27).

New England is 4-3 against the spread, and 3-4 overall, at home.
The Patriots are 3-2 ATS as 2.5-point favorites or greater at home.
In seven home games this season, New England has gone over the total four times.
This season, Patriots home games average 45.4 points, 1.9 more than this outing's over/under (43.5).
Away from home, Buffalo is 4-3 overall and 4-3 against the spread.
This season, as 2.5-point underdogs or more away from home, the Bills are 3-2 ATS.
This year, in seven road games, Buffalo has gone over the total four times.
This season, Bills away games average 50.3 points, 6.8 more than this outing's over/under (43.5).