Los Angeles Rams vs. San Francisco 49ers NFL Week 10 Odds, Plays and Insights

Nov 12, 2021

Check out odds, plays and more for the Los Angeles Rams vs. San Francisco 49ers NFL Week 10 matchup on November 15, 2021.

The Los Angeles Rams (7-2) face an NFC West matchup in Week 10 against the San Francisco 49ers (3-5).

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Odds for Rams vs. 49ers

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Los Angeles' games this season have gone over 49 points five of 11 times.
San Francisco's games have gone over 49 points in five of 10 chances this season.
Monday's total is 3.1 points lower than the two team's combined 52.1 points per game average.
These two squads combine to surrender 47.1 points per game, 1.9 fewer than this contest's over/under.
The average total in Rams games this season is 50.7, 1.7 points more than Monday's total of 49.
In 2020, games involving the 49ers have averaged a total of 46.8 points, 2.2 fewer than this game's set over/under.

Los Angeles has five wins against the spread in nine games this year.
The Rams have been favored by 3.5 points or more eight times this season and have covered the spread in two of them.
Los Angeles has gone over the point total in 45.5% of its opportunities this year (five times in 11 games with a set point total).
The Rams score 3.7 more points per game (29.0) than the 49ers allow (25.3).
Los Angeles is 5-4 against the spread and 7-0 overall in games when it puts up more than 25.3 points.
The Rams average 61.2 more yards per game (399.3) than the 49ers allow per contest (338.1).
When Los Angeles churns out over 338.1 yards, the team is 5-6 against the spread and 7-2 overall.
The Rams have turned the ball over four more times (9 total) than the 49ers have forced a turnover (5) this season.
Click over to SISportsbook and find the latest spread, moneyline and total for Los Angeles' matchup with the 49ers.

San Francisco has played eight games, with three wins against the spread.
This season, the 49ers are winless ATS when entering a game as an underdog of 3.5 points or more.
San Francisco's games this season have gone over the total in five out of 10 opportunities (50%).
The 49ers average just 1.3 more points per game (23.1) than the Rams give up (21.8).
When San Francisco scores more than 21.8 points, it is 2-2 against the spread and 2-1 overall.
The 49ers average only 17.4 more yards per game (365.6) than the Rams allow (348.2).
When San Francisco piles up more than 348.2 yards, the team is 2-2 against the spread and 2-1 overall.
The 49ers have 14 giveaways this season, while the Rams have 14 takeaways.

San Francisco has not covered the spread at home, and is 0-5 overall there, this year.
At home, as 3.5-point underdogs or more, the 49ers are winless ATS (0-4).
San Francisco has hit the over in three of five games at home this year.
This season, 49ers home games average 47.8 points, 1.2 fewer than this contest's over/under (49).
Los Angeles is 3-2 against the spread, and 5-0 overall, on the road.
The Rams have one win ATS (1-2) as 3.5-point favorites or more away from home.
Los Angeles has gone over the total twice in five away games this season.
The average point total in Rams away games this season is 49.4 points, 0.4 more than this contest's over/under (49).