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Kansas City Chiefs vs. Buffalo Bills NFL Week 5 Odds, Plays and Insights

Check out odds, plays and more for the Kansas City Chiefs vs. Buffalo Bills NFL Week 5 matchup on October 10, 2021.

Oct 3, 2021; Philadelphia, Pennsylvania, USA; Kansas City Chiefs head coach Andy Reid during the fourth quarter of a game against the Philadelphia Eagles at Lincoln Financial Field. Mandatory Credit: Bill Streicher-USA TODAY Sports

The Buffalo Bills (3-1) take a three-game winning streak into a matchup with the Kansas City Chiefs (2-2) on Sunday, October 10, 2021 at GEHA Field at Arrowhead Stadium. Kansas City is a 3.5-point favorite in the game.

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Odds for Chiefs vs. Bills

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Chiefs stats and trends

  • So far this season Kansas City has one win against the spread.
  • This season, the Chiefs have just one against the spread win in four games as a favorite of 3.5 points or more.
  • Kansas City's games this year have hit the over on three of four set point totals (75%).
  • The Chiefs average 33.5 points per game, 22.5 more than the Bills allow per matchup (11).
  • Kansas City is 1-3 against the spread and 2-2 overall this season when the team records more than 11 points.
  • The Chiefs collect 210.7 more yards per game (427.5) than the Bills give up per outing (216.8).
  • Kansas City is 1-3 against the spread and 2-2 overall when the team churns out over 216.8 yards.
  • The Chiefs have seven giveaways this season, while the Bills have 11 takeaways.
  • Click over to SISportsbook and find the latest spread, moneyline and total for Kansas City's matchup with the Bills.

Bills stats and trends

  • Buffalo has three wins against the spread in four games this year.
  • Buffalo's games this season have hit the over on one of four set point totals (25%).
  • The Bills rack up the same number of points per game that the Chiefs give up (31.3).
  • Buffalo is 3-0 against the spread and 3-0 overall in games when it records more than 31.3 points.
  • The Bills rack up 33.8 fewer yards per game (404) than the Chiefs allow per matchup (437.8).
  • Buffalo is 2-0 against the spread and 2-0 overall when the team piles up more than 437.8 yards.
  • The Bills have four turnovers this season, equal to the number of takeaways for the Chiefs.

Home and road insights

  • At home, as 3.5-point favorites or more, the Chiefs are winless ATS (0-2).
  • The Bills are unbeaten ATS (1-0) as 3.5-point underdogs or more away from home.

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