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Buffalo Bills vs. Tennessee Titans NFL Week 6 Odds, Plays and Insights

Check out odds, plays and more for the Buffalo Bills vs. Tennessee Titans NFL Week 6 matchup on October 18, 2021.

Oct 3, 2021; Orchard Park, New York, USA; Buffalo Bills running back Devin Singletary (26) finds a hole to run against the Houston Texans in the fourth quarter at Highmark Stadium. Mandatory Credit: Mark Konezny-USA TODAY Sports

The AFC East-leading Buffalo Bills (4-1) square off against the AFC South-leading Tennessee Titans (3-2) on Monday, October 18, 2021 at Nissan Stadium. Buffalo is a 5.5-point favorite in the matchup. A 54.5-point over/under is set for the game.

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Odds for Bills vs. Titans

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Over/under insights

  • Buffalo and its opponents have gone over the current 54.5-point total in three of six games this season.
  • Tennessee has combined with its opponents to score more than 54.5 points in two games this season.
  • The combined points per game average of the two teams, 60.8, is 6.3 points above Monday's over/under.
  • The 38.8 combined points per game that these two squads have allowed this season are 15.7 fewer than the 54.5 total in this contest.
  • The average total in Bills games this season is 49.0, 5.5 points fewer than Monday's over/under of 54.5.
  • The 49.6 PPG average total in Titans games this season is 4.9 points fewer than this game's over/under.

Bills stats and trends

  • Buffalo has played five games, with five wins against the spread.
  • The Bills have been favored by 5.5 points or more three times this season and have covered the spread in two of them.
  • Buffalo's games this year have gone over the total in two out of six opportunities (33.3%).
  • This year, the Bills average 8.4 more points per game (34.4) than the Titans give up (26).
  • Buffalo is 5-0 against the spread and 4-0 overall this season when the team notches more than 26 points.
  • The Bills average 33 more yards per game (410.4) than the Titans give up per outing (377.4).
  • In games that Buffalo piles up over 377.4 yards, the team is 4-0 against the spread and 3-0 overall.
  • This year, the Bills have turned the ball over four times, while the Titans have forced four.
  • Click over to SISportsbook and find the latest spread, moneyline and total for Buffalo's matchup with the Titans.

Titans stats and trends

  • In Tennessee's five games this year, it has three wins against the spread.
  • This year, the Titans won ATS in their only game as an underdog of 5.5 points or more.
  • Tennessee's games this season have hit the over on three of five set point totals (60%).
  • The Titans rack up 13.6 more points per game (26.4) than the Bills give up (12.8).
  • Tennessee is 3-2 against the spread and 3-2 overall in games when it puts up more than 12.8 points.
  • The Titans average 137.4 more yards per game (389.2) than the Bills allow (251.8).
  • When Tennessee totals more than 251.8 yards, the team is 3-1 against the spread and 3-1 overall.
  • The Titans have turned the ball over seven times, eight fewer times than the Bills have forced turnovers (15).

Home and road insights

  • Titans home games this season average 50.5 total points, 4.0 fewer than this outing's over/under (54.5).
  • Buffalo is 3-0 overall, and unbeaten against the spread, in away games.
  • In three away games this season, Buffalo has hit the over once.
  • Bills away games this season average 52.3 total points, 2.2 fewer than this contest's over/under (54.5).

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