Buffalo Bills vs. New Orleans Saints NFL Week 12 Odds, Plays and Insights

Nov 23, 2021

Check out odds, plays and more for the Buffalo Bills vs. New Orleans Saints NFL Week 12 matchup on November 25, 2021.

The New Orleans Saints (5-5) will attempt to end a three-game slide when they meet the Buffalo Bills (6-4) in Week 12.

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Odds for Bills vs. Saints

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Buffalo and its opponents have combined to score more than 46.5 points in five of 10 games this season.
New Orleans has combined with its opponents to score more than 46.5 points in five of 10 games this season.
Thursday's over/under is 8.1 points lower than the two team's combined 54.6 points per game average.
The 39.4 combined points per game that these two squads have allowed this season are 7.1 fewer than the 46.5 total in this contest.
The average total in Bills games this season is 49.3, 2.8 points more than Thursday's total of 46.5.
The 46.5 total in this game is 2.2 points higher than the 44.3 average total in Saints games this season.

Buffalo has six wins against the spread in 10 games this season.
The Bills have been favored by 4.5 points or more eight times this season and are 4-4 ATS in those games.
Buffalo's games this year have hit the over five times in 10 opportunities (50%).
The Bills put up 7.7 more points per game (29.5) than the Saints surrender (21.8).
Buffalo is 6-1 against the spread and 6-1 overall this season when the team records more than 21.8 points.
The Bills collect 391.7 yards per game, 49.7 more yards than the 342.0 the Saints give up per matchup.
In games that Buffalo piles up more than 342.0 yards, the team is 5-2 against the spread and 5-2 overall.
The Bills have 14 turnovers this season, equal to the number of takeaways for the Saints.
Click over to SISportsbook and find the latest spread, moneyline and total for Buffalo's matchup with the Saints.

In New Orleans' 10 games this year, it has five wins against the spread.
New Orleans' games this year have gone over the total in six out of 10 opportunities (60%).
The Saints score 25.1 points per game, 7.5 more than the Bills allow (17.6).
When New Orleans puts up more than 17.6 points, it is 5-3 against the spread and 4-4 overall.
The Saints rack up 37.6 more yards per game (321.3) than the Bills give up (283.7).
In games that New Orleans amasses more than 283.7 yards, the team is 4-4 against the spread and 4-4 overall.
The Saints have turned the ball over 11 times, 13 fewer times than the Bills have forced turnovers (24).

New Orleans has two wins against the spread, and is 2-2 overall, at home this season.
The Saints are winless ATS (0-2) as 4.5-point underdogs or greater at home.
This year, in four games at home, New Orleans has hit the over three times.
This season, Saints home games average 45.8 points, 0.7 fewer than this contest's over/under (46.5).
On the road, Buffalo is 3-2 overall and 3-2 against the spread.
On the road, the Bills have one win ATS (1-2) as 4.5-point favorites or more.
Buffalo has hit the over in three of five road games this season.
The average point total in Bills away games this season is 50.9 points, 4.4 more than this outing's over/under (46.5).