The Ireland coaching group have named their matchday squad, that includes one new cap, to face Fiji at Aviva Stadium on Saturday.
Munster's Chris Farrell is set to win his first cap alongside Stuart McCloskey in a new-look centre partnership.
Andrew Conway moves to full-back with Darren Sweetnam, who won his first cap last week, starting for the first time. David Kearney returns to the side to complete the back three.
Kieran Marmion will partner Joey Carbery in the half-backs.
Up front Rhys Ruddock reprises his summer tour role as captain to lead the side. He is joined in the back-row by Jordi Murphy, who lined out for the Barbarians last week and Jack Conan.
Ultan Dillane joins Devin Toner in the engine room of the second-row while Jack McGrath returns to duty in the front-row where he is joined by Rob Herring and Andrew Porter.
James Tracy, who made his debut this time last year against Canada and Kieran Treadwell, who won his first cap on the summer tour are included in the replacements.
Cian Healy, Tadhg Furlong, CJ Stander and Robbie Henshaw are inlcuded from last week's starting XV with Luke McGrath and Ian Keatley completing the replacements.
Ireland: 15 Andrew Conway, 14 Darren Sweetnam, 13 Chris Farrell, 12 Stuart McCloskey, 11 Dave Kearney, 10 Joey Carbery, 9 Kieran Marmion, 8 Jack Conan, 7 Jordi Murphy, 6 Rhys Ruddock (c), 5 Devin Toner, 4 Ultan Dillane, 3 Andrew Porter, 2 Rob Herring, 1 Jack McGrath
Replacements: 16 James Tracy, 17 Cian Healy, 18 Tadhg Furlong, 19 Kieran Treadwell, 20 CJ Stander, 21 Luke McGrath, 22 Ian Keatley, 23 Robbie Henshaw
Date: Saturday, November 18
Venue: Aviva Stadium
Kick-off: 17:30 GMT
Referee: Paul Williams (New Zealand)
Assistant referees: Angus Gardner (Australia), Alex Ruiz (France)
Television match official: David Grashoff (England)
Photo credit: Irish Rugby official website
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