Wales' Hallam Amos is a major doubt for the start of the Six Nations after suffering an ankle injury in Dragons' Boxing Day loss to Cardiff Blues.
The 23-year-old wing could be sidelined for up to six weeks if he needs surgery.
"We're just waiting to see if we can rehab that or do we need an operation," Dragons coach Bernard Jackman told the BBC.
"We're just liaising with the Wales medics to see what's the best course of treatment. Five or six weeks is the pessimistic outlook."
Wales begin the 2018 Six Nations against Scotland in Cardiff on Saturday, 3 February and Jackman added: "Hopefully we can get him back for the Six Nations."
Amos was sidelined for most of the 2016-17 season with a shoulder injury but won a Wales recall for the 2017 November internationals, coming off the bench in the opening game against Australia and then starting against Georgia, New Zealand and South Africa.
Jackman was speaking after the Dragons lost 22-9 at home to the Ospreys on New Year's Eve in the PRO14 Welsh derby.
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